Sömn och mottaglighet för förkylningsvirus

[Trance]

Disclamer: Jag vet inte om det postats och även om det inte är kost i sig så kändes det som det passades bäst här.


Sleep Habits and Susceptibility to the Common Cold
Sheldon Cohen, PhD; William J. Doyle, PhD; Cuneyt M. Alper, MD; Denise Janicki-Deverts, PhD; Ronald B. Turner, MD
Arch Intern Med. 2009;169(1):62-67.

Background Sleep quality is thought to be an important predictor of immunity and, in turn, susceptibility to the common cold. This article examines whether sleep duration and efficiency in the weeks preceding viral exposure are associated with cold susceptibility.

Methods A total of 153 healthy men and women (age range, 21-55 years) volunteered to participate in the study. For 14 consecutive days, they reported their sleep duration and sleep efficiency (percentage of time in bed actually asleep) for the previous night and whether they felt rested. Average scores for each sleep variable were calculated over the 14-day baseline. Subsequently, participants were quarantined, administered nasal drops containing a rhinovirus, and monitored for the development of a clinical cold (infection in the presence of objective signs of illness) on the day before and for 5 days after exposure.

Results There was a graded association with average sleep duration: participants with less than 7 hours of sleep were 2.94 times (95% confidence interval [CI], 1.18-7.30) more likely to develop a cold than those with 8 hours or more of sleep. The association with sleep efficiency was also graded: participants with less than 92% efficiency were 5.50 times (95% CI, 2.08-14.48) more likely to develop a cold than those with 98% or more efficiency. These relationships could not be explained by differences in prechallenge virus-specific antibody titers, demographics, season of the year, body mass, socioeconomic status, psychological variables, or health practices. The percentage of days feeling rested was not associated with colds.

Conclusion Poorer sleep efficiency and shorter sleep duration in the weeks preceding exposure to a rhinovirus were associated with lower resistance to illness.
http://archinte.ama-assn.org/cgi/con...tract/169/1/62

En dell som hade en lite längre artikel som var lite intressant. Postar abstract:

Abstract
Sleep is an enigma. Why animals forgo eating and reproducing, while potentially increasing their risk of predation remains unknown. Although some may question whether all animals sleep, it is clear that all living organisms possess defenses against attack by pathogens. Immune responses of humans and animals are impaired by sleep loss, and responses to immune challenge include altered sleep. Thus, sleep is hypothesized to be a component of the acute phase response to infection and to function in host defense. Examining phylogenetic relationships among sleep parameters, components of the mammalian immune system and resistance to infection may provide insight into the evolution of sleep and lead to a greater appreciation for the role of sleep in host defense.
http://www.biomedcentral.com/1471-2148/9/8

[Mr.Cosybear]

Intressant! Nu är inte jag någon expert alls men det första som slår mig är att kan inte 14 dagar vara en för kort period att undersöka? Det jag tänker främst på är att det kanske tar längre tid för de som sover längre att utveckla symptom, men det kanske inte är så?

[Mental]

Ursprungligen postat av Mr.Cosybear

Intressant! Nu är inte jag någon expert alls men det första som slår mig är att kan inte 14 dagar vara en för kort period att undersöka? Det jag tänker främst på är att det kanske tar längre tid för de som sover längre att utveckla symptom, men det kanske inte är så?

Mjo, men de exponerade dem för virus isolerade och höll de senare under övervakning

During the prechallenge baseline period, we assessed virusspecific
neutralizing antibody titers, demographics, and height
and weight in healthy volunteers. We also interviewed the volunteers
about their sleep quality during the previous night on
14 consecutive days. Other interview and questionnaire data collected
during the prechallenge baseline included health practices
and psychological factors. The participants were then quarantined
in separate rooms, exposed to RV-39, and monitored for
5 days to assess infection and signs and symptoms of illness.

[Doctor Snuggles]

Min personliga n=1 erfarenhet stämmer in på detta resultat.
Lägg på hård styrketräning och/eller stress så kommer förkylningen med cykelbud.