These compounds are absorbed by the body during digestion with about 30% efficiency. Browning reactions (usually Maillard type reactions) are evidence of pre-formed glycations. Indeed, sugar is often added to products such as french fries and baked goods to enhance browning. Glycation may also contribute to the formation of acrylamide,[2] a potential carcinogen, during cooking. Until recently, it was thought that exogenous glycations and AGEs were negligible contributors to inflammation and disease states, but recent work has shown that they are important.[3] Although most of the research on this topic has been done with reference to diabetes, these results are likely to be important for all people, as exogenous AGEs are implicated in the initiation of retinal dysfunction, cardiovascular diseases, type II diabetes, and many other age-related chronic diseases.
Food manufacturers have added AGEs to foods, especially in the last 50 years, as flavor enhancers and colorants to improve appearance.[4] Foods with significant browning, caramelization, or directly added preformed AGEs can be exceptionally high in these proinflammatory and disease-initiating compounds. A very partial listing of foods with very high exogenous AGEs includes donuts, barbecued meats, cake, and dark colored soda pop.
Citat:
The formation and accumulation of advanced glycation endproducts (AGEs) has been implicated in the progression of age-related diseases. AGEs have been implicated in Alzheimer's Disease, cardiovascular disease, and stroke. The mechanism by which AGEs induce damage is through a process called cross-linking that causes intracellular damage and apoptosis. They form photosensitizers in the crystalline lens, which has implications for cataract development. Reduced muscle function is also associated with AGEs.
The total state of oxidative and peroxidative stress on the healthy body, and the accumulation of AGE-related damage is proportional to the dietary intake of exogenous (preformed) AGEs, the consumption of sugars with a propensity towards glycation such as fructose and galactose.
Det fungerade inte att klistra in tabellen som den var, men det står i alla fall att t ex cola light, eller lightläsk innehåller 9.500 "AGE units / cup"
Är det här med AGE's nytt på något sätt? Det stod också att ett stekt ägg som blandas blir "200 times more AGE immunoreactive". Betyder det här att läsk, brynta livsmedel mm är giftiga? Vad ska man dra för slutsatser av det här?
Din slutsats bör vara att inte bränna köttet i stekpannan. Nöj dig med att ägget stelnar och inte blir svart i kanterna. Sockerkulör i cola är jag inte lika säker på eftersom det är karamelisering och inte brunfärgningsprodukter. Skadar inte att byta colan mot 7Up eller Fanta ibland.
Du får söka på "AGE" på Kolozzeum får du massor av träffar.
__________________
Sverker
Chairmaster of
Kolozzeum Chemistry Guild.