Effekt av kolhydratlösning av olika koncentration på markörer för nedbrytning

[King Grub]

The purpose of this study was to investigate the effect of ingestion of fluids with different carbohydrate concentrations (0 %, 1.5 % and 7 %) on the acute immune stress responses after high-intensity long-distance running. Continuous 18-20 kilometers run was performed at 75% of maximal oxygen uptake with carbohydrate supplementation (CHO7%, 7% carbohydrate solution) and low-carbohydrate supplementation (lowCHO1.5%, 1.5% carbohydrate solution) in a randomized, double-blind, placebo (PLA) controlled design. Seven recreational runners (four males and three females) completed all three trials. Blood was collected at baseline (PRE) and immediately after the run (POST). The running task induced significant (p<0.05) increases in leukocyte (WBC), neutrophil and interleukin-6 (IL-6) counts in every trial. There was a significant (p<0.05) increase in cortisol with PLA and lowCHO1.5% but not with CHO7%. Increase in total leukocyte and neutrophil concentration was significantly lower with CHO7% compared to PLA (p<0.05). Post-exercise IL-6 levels were significantly elevated when compared to baseline in all conditions (p<0.05). IL-6 concentrations did not differ significantly between trials. LowCHO1.5% sport drink did not significantly differ from PLA in measured variables, which indicated that the amount and rate of carbohydrate ingestion (15 g, 10 g [BULLET OPERATOR] h) in low carbohydrate sport drink was not enough to significantly protect from the stress induced by high-intensity long-distance running whereas, the ingestion of CHO7% (45 g [BULLET OPERATOR] h) blunted the significant cortisol response and significantly decreased the leukocyte response.

J Strength Cond Res. 2014 May 2. Effects of Carbohydrate Ingestion on Acute Leukocyte, Cortisol and IL-6 Response in High-Intensity Long-Distance Running.