Cissus

[EiseltUK]

Vad tror ni om det här?

A recent study was undertaken to investigate the role of Cissus quadrangularis in stimulating gonadotropins and to establish its use in male/female reproductive disorders as well as a safe alternative to synthetic androgens.*

50 Human healthy adult male volunteers were selected and each was given 120 capsules each containing either 150mg of Cissus quadrangularis (standardized to 5% keto-steroids) or 150mg microcrystalline cellulose. The bottles were coded and randomly distributed amongst the volunteers. Each volunteer was prescribed 1 capsule TDS ½ hour before meals.

Blood was drawn from each volunteer at day 1 and basal rates of testosterone, LH and FSH were determined. The volunteers were then called back at day 30 and day 60 for a second round of blood assay. The results are presented below:


http://www.soylabs.com/img/chart-cissus-testosterone.gif


Cissus är en dokumenterad kortisolantagonist. Skulle kortisolhämningen kunna vara orsaken till att LH ökar?

[Tuniz]

vad... gör Cissus? :confused:

Ökar testosteronproduktionen?

[EiseltUK]

Det används av tränande för att det är bra vid olika typer av problem med leder, muskelfästen osv men också för att det ska ha anti-katabola/ indirekt anabola egenskaper.

[Snakeyes]

En snabb sökning pekar på att det finns ett samband, se t ex:

Endocrine Reviews, Vol 7, 75-88, Copyright © 1986 by Endocrine Society

Gonadal regulation of hypothalamic gonadotropin-releasing hormone release in primates
TM Plant


This review has examined, in primates, the action of sex steroids on the neural timing mechanism that governs the intermittent release of GnRH by the hypothalamus, the so-called GnRH pulse generator. Determinants of hypothalamic GnRH pulse generator frequency have generally been examined indirectly by monitoring moment to moment fluctuations in circulating LH concentrations. Studies using this approach have led to the hypothesis that negative feedback control of LH secretion by the testes is mediated by the action of T, or of one of its metabolites, to retard the frequency of the GnRH pulse generator. P also appears capable of decelerating GnRH pulse frequency during the luteal phase of the menstrual cycle, but the physiological significance of this phenomenon remains to be clarified. To date, a cognate action of E2 on the GnRH pulse generator has not been described. Because of limitations in contemporary technology, the factors underlying amplitude modulation of the GnRH pulse generator are less well understood. In addition to the ability of certain sex steroids to decelerate the frequency of pulsatile GnRH discharge, E2 and P appear capable of facilitating the secretion of this hypothalamic releasing factor. However, the increase in GnRH pulse frequency and/or GnRH pulse amplitude that must underlie these stimulatory actions remains to be fully defined. An inhibitory action of high levels of circulating cortisol on the hypothalamic GnRH pulse generator has also been noted.

[Snakeyes]

Lämpliga sökord borde inkludera cortisol, GnRH, luteinizing hormone etc.

Se även Human Reproduction Update 1996, Vol. 2, No. 6 pp. 507–518

[Fairing]

Det används av tränande för att det är bra vid olika typer av problem med leder, muskelfästen osv men också för att det ska ha anti-katabola/ indirekt anabola egenskaper.

Om det skulle hjälpa mina leder och muskelfästen så köper jag hela första batchen av dig:D

[Mental]

Ett pro-hormon då eller?

[EiseltUK]

Om det skulle hjälpa mina leder och muskelfästen så köper jag hela första batchen av dig:D


Okej då bokar jag den åt dig. Du får 10% storköpsrabatt. :D

[olle lindblad]

Vad är Cissus quadrangularis?

[EiseltUK]

Cissus är en växt som är vanligt i bl a Indien. Innehåller ketosteroider som man antar är de aktiva ämnena.

Finns även någon studie som visade att försökspersoner gick ned i vikt (kan bero på antikortisoleffekten).