Muskel- och njurskador av högintensiv styrketräning

[King Grub]

PURPOSE:

High-intensity interval resistance training (HIIRT) is an increasingly popular exercise program that provides positive results with short sessions. This study aimed to evaluate whether an HIIRT session causes muscle and kidney damage.

METHODS:

Fifty-eight healthy volunteers (median age 24 years, 50% women) participated in this study and performed a HIIRT session. The Borg CR10 scale for pain (CR10P) and blood and urine samples were collected before (baseline) and 2 and 24 hours after the HIIRT session. Blood samples were analyzed for serum creatinine (SCr), creatine kinase (CK) and myoglobin. Urine samples were assessed for creatinine, neutrophil gelatinase-associated lipocalin, interleukin 18, calbindin, microalbuminuria, trefoil factor-3 and β-2 microglobulin.

RESULTS:

CR10P had a significant increase at 2 and 24 hours post-workout, and CK increased significantly at 2 hours and increased further at 24 hours. Myoglobin increased significantly at 2 hours and remained elevated at 24 hours. SCr increased modestly but significantly at 24 hours only in men. Three men met the KDIGO diagnostic criteria for acute kidney injury. The urinary kidney injury biomarkers increased significantly at 2 hours and returned to the baseline values 24 hours after HIIRT.

CONCLUSIONS:

A single HIIRT session caused early and significant elevations in CK, myoglobin, SCr, microalbuminuria and urinary biomarkers indicative of kidney tubular injury, suggesting the occurrence of muscle and kidney damage.

PLoS One. 2018 Nov 6;13(11):e0205791. High intensity resistance training causes muscle damage and increases biomarkers of acute kidney injury in healthy individuals.

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205791

[Diomedea exulans]

HIT och HIIT har man hört, men HIIRT, den var ny.

[Termy]

Program:
The individuals performed four minutes of HIIRT (squat exercises in the Tabata style). The HIIRT session consisted of eight sets of squats performed with the fastest speed and highest number of repetitions achievable for 20 seconds with 10 seconds of rest between sets.

19 % som hade så höga nivåer av CK att det klassades som rhabdomyolys:
In the current study, HIIRT induced early and progressive muscle injury, as shown by the muscle soreness, and significant changes in serum CK and myoglobin in the majority of the individuals assessed, with CK elevation indicative of rhabdomyolysis in 19% of the participants.

Kuriosa:
European epidemiological studies found that the number of patients admitted to the hospital with exercise-induced rhabdomyolysis increased strikingly from 2010–2011 to 2014–2015. The majority of patients were referred as a result of strength training at fitness centers, with up to 6% of the patients developing AKI. The authors hypothesized that this observed growth in the frequency of exercise-induced rhabdomyolysis might be due to the culture of high-intensity training and increased societal pressure to exercise

Vad är det som hänt här? Explosion i crossfitutövande?

[svenbanan]

Vad är det som hänt här? Explosion i crossfitutövande?

Säkerligen.

Lukas Högbeg, vår svenske Crossfitstjärna åkte väl på rhabdo häromåret i en crossfittävling om jag inte missminner mig.

[speedy83]

Rhabdo drabbade väl även ultralöparen Johhny H i något bergslopp vill jag minnas typ UTMB eller dyl.

[Rahf]

Program:


19 % som hade så höga nivåer av CK att det klassades som rhabdomyolys:


Kuriosa:


Vad är det som hänt här? Explosion i crossfitutövande?

Säkerligen.

Lukas Högbeg, vår svenske Crossfitstjärna åkte väl på rhabdo häromåret i en crossfittävling om jag inte missminner mig.

Strukturen på studiens övningsutförande är väldigt lik crossfit-metodiken, så rhabdo är inte förvånande.

För övrigt verkar det finnas en artikel om Johnny H. Kanske initialerna är detsamma, även om han vill vara anonym? https://www.irunfar.com/2018/02/break-it-down-exertional-rhabdomyolysis-in-ultramarathons.html

[Termy]

Ändå både fascinerande och skrämmande att det kan ske så mycket på bara ett pass vid en hög och/eller ovan träningsvolym. Undrar hur det hade sett ut om samma testgrupp hade fått träna mot just den doseringen fast med en gradvis upptrappning på X veckor/månader.