King Grub
2009-12-03, 10:48
PURPOSE:: Dietary supplementation with polyphenols, particularly ellagitannins, may attenuate the muscular damage experienced after eccentric exercise producing delayed onset muscle soreness (DOMS). The purpose of this study was to determine if ellagitannin supplementation from Wonderful variety pomegranate extract (POMx) improved recovery of skeletal muscle strength following eccentric exercise.
METHODS:: Recreationally active males were randomized into a crossover design with either pomegranate extract (POMx) or placebo (PLA), each given over a period of nine days. To produce DOMS, subjects performed 2 sets of 20 maximal eccentric elbow flexion exercises with one arm. Maximal isometric elbow flexion strength and muscle soreness as well as serum measures of creatine kinase, myoglobin, interleukin-6, and c-reactive protein were made at baseline and 2, 24, 48, 72, and 96 h post-exercise.
RESULTS:: With both treatments, strength was similarly reduced 2 h after exercise (i.e.; 72% of baseline) and recovery of strength was incomplete after 96 h (i.e.; 91% of baseline). However, strength was significantly higher in POMx compared to PLA at 48 h (85.4 +/- 2.5% and 78.3 +/- 2.6%; p= 0.01) and 72 h (88.9 +/- 2.0% and 84.0 +/- 2.0%; p= 0.009) post-exercise. Serum markers of inflammation and muscle damage did not provide insight regarding possible mechanisms.
CONCLUSION:: Supplementation with ellagitannins from pomegranate extract significantly improves recovery of isometric strength 2-3 days following damaging eccentric exercise.
Med Sci Sports Exerc. 2009 Nov 23. Ellagitannin Consumption Improves Strength Recovery 2-3 Days after Eccentric Exercise.
METHODS:: Recreationally active males were randomized into a crossover design with either pomegranate extract (POMx) or placebo (PLA), each given over a period of nine days. To produce DOMS, subjects performed 2 sets of 20 maximal eccentric elbow flexion exercises with one arm. Maximal isometric elbow flexion strength and muscle soreness as well as serum measures of creatine kinase, myoglobin, interleukin-6, and c-reactive protein were made at baseline and 2, 24, 48, 72, and 96 h post-exercise.
RESULTS:: With both treatments, strength was similarly reduced 2 h after exercise (i.e.; 72% of baseline) and recovery of strength was incomplete after 96 h (i.e.; 91% of baseline). However, strength was significantly higher in POMx compared to PLA at 48 h (85.4 +/- 2.5% and 78.3 +/- 2.6%; p= 0.01) and 72 h (88.9 +/- 2.0% and 84.0 +/- 2.0%; p= 0.009) post-exercise. Serum markers of inflammation and muscle damage did not provide insight regarding possible mechanisms.
CONCLUSION:: Supplementation with ellagitannins from pomegranate extract significantly improves recovery of isometric strength 2-3 days following damaging eccentric exercise.
Med Sci Sports Exerc. 2009 Nov 23. Ellagitannin Consumption Improves Strength Recovery 2-3 Days after Eccentric Exercise.