Långvarig nedreglering av TEE, NREE och REE lång tid efter viktnedgång.

[King Grub]

After weight loss, total energy expenditure—in particular, energy expenditure at low levels of physical activity—is lower than predicted by actual changes in body weight and composition. An important clinical issue is whether this reduction, which predisposes to weight regain, persists over time.

We aimed to determine whether this disproportionate reduction in energy expenditure persists in persons who have maintained a body-weight reduction of ≥10% for >1 y.

Seven trios of sex- and weight-matched subjects were studied in an in-patient setting while receiving a weight-maintaining liquid formula diet of identical composition. Each trio consisted of a subject at usual weight (Wtinitial), a subject maintaining a weight reduction of ≥10% after recent (5–8 wk) completion of weight loss (Wtloss-recent), and a subject who had maintained a documented reduction in body weight of >10% for >1 y (Wtloss-sustained). Twenty-four-hour total energy expenditure (TEE) was assessed by precise titration of fed calories of a liquid formula diet necessary to maintain body weight. Resting energy expenditure (REE) and the thermic effect of feeding (TEF) were measured by indirect calorimetry. Nonresting energy expenditure (NREE) was calculated as NREE = TEE – (REE +TEF).

TEE, NREE, and (to a lesser extent) REE were significantly lower in the Wtloss-sustained and Wtloss-recent groups than in the Wtinitial group. Differences from the Wtinitial group in energy expenditure were qualitatively and quantitatively similar after recent and sustained weight loss.

Declines in energy expenditure favoring the regain of lost weight persist well beyond the period of dynamic weight loss.

American Journal of Clinical Nutrition, Vol. 88, No. 4, 906-912, October 2008.

http://www.ajcn.org/cgi/content/full/88/4/906

[Scratch89]

Frågan är ju var energin sparas in ifrån. Lägre kroppstemperatur? Mindre muskelmassa?

[Guddi]

Tack för den Gruben, jag har letat efter någon studie som tittat på energiförbrukninge lång tid efter en viktnedgång. Du vet inga fler liknande studier?

[Eddie Vedder]

Tack för den Gruben, jag har letat efter någon studie som tittat på energiförbrukninge lång tid efter en viktnedgång. Du vet inga fler liknande studier?

Du kan få referenslistan om du vill (fast den har du kanske redan tillgång till iofs:)). Jag tog en kort titt men tyvärr finns mest kortare studier som du säger. Det är lite det som studien bygger på, d.v.s. bristen på mer långsiktiga studier i ämnet.

In lean and obese adults studied during or shortly (3 mo)
after weight loss, our group (1– 6) and others (7–15) have shown
significant reductions in energy expenditure (EE) beyond those
predicted solely on the basis of changes in weight and body
composition. Fewer investigators have examined the consequences
of longer-term maintenance of reduced weight on measures
of EE (16). Such studies are important to distinguish between
possible “carryover” persistence of declines in EE
characterizing the period of active weight loss and longer biological
responses to decreased energy stores per se. Some authors
have suggested that this reduction in EE persists for prolonged
periods after weight loss (1, 12, 16–22), whereas others (23–27)
have reported no changes in EE corrected for changes in body mass and composition at any point after weight reduction. The
question of whether declines in EE after weight loss persist in the
long term is critical to understanding the physiologic basis for the
high rate of recidivism to obesity after otherwise successful
weight reduction (28, 29).

[Guddi]

Du kan få referenslistan om du vill (fast den har du kanske redan tillgång till iofs:)). Jag tog en kort titt men tyvärr finns mest kortare studier som du säger. Det är lite det som studien bygger på, d.v.s. bristen på mer långsiktiga studier i ämnet.Jag ladda ner den och la den på skrivbordet, mer än så blev det inte och det blir väl inte förrän nästa vecka jag tittar igenom den. Tack för hjälpen Eddie...

Angående ämnet så har jag en studie någonstans på datorn där man såg att kvinnor som gått ner mer än 10 kg i vikt under sin livstil hade en lägre metabolism jämnviktiga kvinnor. I den studien visste man dock inte om det berodde på en lägre metabolism från början eller för att de vägt mer tidigare. Det kanske man inte gör i denna heller?