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Visa fullständig version : Q10 och prestationsförmåga.


King Grub
2008-07-26, 15:45
To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals.

Twenty-two aerobically trained and nineteen untrained male and female subjects (26.1 ± 7.6 yrs, 172 ± 8.7 cm, 73.5 ± 17 kg, and 21.2 ± 7.0%) were randomized to ingest in a double-blind manner either 100 mg of a dextrose placebo (CON) or a fast-melt CoQ10 supplement (CoQ10) twice a day for 14-days. On the first day of supplementation, subjects donated fasting blood samples and a muscle biopsy. Subjects were then given 200 mg of the placebo or the CoQ10 supplement. Sixty minutes following supplement ingestion, subjects completed an isokinetic knee extension endurance test, a 30-second wingate anaerobic capacity test, and a maximal cardiopulmonary graded exercise test interspersed with 30-minutes of recovery. Additional blood samples were taken immediately following each exercise test and a second muscle biopsy sample was taken following the final exercise test. Subjects consumed twice daily (morning and night), 100 mg of either supplement for a period of 14-days, and then returned to the lab to complete the same battery of tests. Data was analyzed using repeated measures ANOVA with an alpha of 0.05.

Plasma CoQ10 levels were significantly increased following 2 weeks of CoQ10 supplementation (p < 0.001); while a trend for higher muscle CoQ10 levels was observed after acute CoQ10 ingestion (p = 0.098). A trend for lower serum superoxide dismutase (SOD) was observed following acute supplementation with CoQ10 (p = 0.06), whereas serum malondialdehyde (MDA) tended to be significantly higher (p < 0.05). Following acute ingestion of CoQ10, plasma CoQ10 levels were significantly correlated to muscle CoQ10 levels; maximal oxygen consumption; and treadmill time to exhaustion. A trend for increased time to exhaustion was observed following 2 weeks of CoQ10 supplementation (p = 0.06).

Acute supplementation with CoQ10 resulted in higher muscle CoQ10 concentration, lower serum SOD oxidative stress, and higher MDA levels during and following exercise. Chronic CoQ10 supplementation increased plasma CoQ10 concentrations and tended to increase time to exhaustion. Results indicate that acute and chronic supplementation of CoQ10 may affect acute and/or chronic responses to various types of exercise.

J Int Soc Sports Nutr. 2008 Mar 4;5:8. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.

http://www.jissn.com/content/pdf/1550-2783-5-8.pdf

kraftsport
2008-08-12, 19:58
Vad betyder det då?

Är det bra eller dåligt? :confused:

King Grub
2008-08-12, 20:51
Är det bra eller dåligt? :confused:

Ja, om du uppskattar minskad oxidativ stress och längre tid till utmattning vid träning, så är det bra. :)

Kräket
2008-08-13, 17:23
Blir man dumförklarad om man frågar vad CoQ10 är för tillskott/ämne?

Per B
2008-08-13, 17:26
Blir man dumförklarad om man frågar vad CoQ10 är för tillskott/ämne?

Ja, om man inte googlar lite själv innan man frågar! ;)

http://en.wikipedia.org/wiki/Coenzyme_Q10

skaparn
2008-08-13, 20:28
Jag tycker det är riktigt kul att man testar det som jag (kanske något okunnigt och felaktigt) klassat som naturläkemdelsmumbojumbo. I'm buying! Kanske.

Dan S
2008-08-13, 23:40
Det är alltså ett "rent" ämne man köper ungefär som "Extreme Q10" eller är det ett ämne vi hittar i produkter med blandat innehåll som rage osv? Behövs det mycket utav detta? 200mg motsvarar ungefär som en alvedon?

EDIT: Alvedon har olika storlek -_- en liten menar jag då.

C.E.J.
2008-08-14, 11:24
Det är alltså ett "rent" ämne man köper ungefär som "Extreme Q10" eller är det ett ämne vi hittar i produkter med blandat innehåll som rage osv? Behövs det mycket utav detta? 200mg motsvarar ungefär som en alvedon?

EDIT: Alvedon har olika storlek -_- en liten menar jag då.

Q10 finns mig veterligen inte i Rage. *dubbelkollar* Nope inget Q10 i det.

Kischen
2008-08-14, 11:54
Kollade runt lite av intresse, nej, brist på intresse eftersom jag är på jobbet;)
100 mgr 2 gånger om dagen? Blir ganska dyrt om inte effekten är stor.

Dom flesta tillskott jag hittade var 30 mgr kapsel.

King Grub
2008-09-18, 10:20
CoQ10 has come to be widely used as a dietary supplement, and daily intake of it has increased in recent years. CoQ10 is produced in all living organisms and is an essential coenzyme for energy synthesis in the mitochondria and an important scavenger of reactive oxygen species.

This is a randomized, double-blind, placebo-controlled experiment to examine the acute effects of a single dose of CoQ10 on the autonomic nervous system (ANS) by using power spectral analysis of HRV and energy metabolism at rest and during low intensity exercise in healthy subjects. Eleven nonsmoking healthy male students (age: 26+/-1 y) volunteered to participate in this experiment. CM5 lead ECG and gas exchange parameters were recorded 5 min before, and 30 min and 60 min after the oral administration of CoQ10 or a placebo. Following this, the subjects exercised using a stationary cycle ergometer for 10 min at 60 rpm with an intensity of 30% of heart rate reserve. During the exercise, the ECG and gas exchange parameters were recorded continuously.

There were no significant differences in heart rate between the CoQ10 and placebo trials at rest or during exercise. With regard to the integrated values of the spectrum, there were no significant differences in the HF power representing parasympathetic activity or LF power representing both sympathetic and parasympathetic nervous activities between the trials at any timepoint. However, during the exercise, HF power and LF power in the CoQ10 trial showed a tendency to increase compared with the placebo trial (p<0.1). Total power representing the over-all ANS activity was significantly increased in the CoQ10 trial during exercise, which implied that autonomic nervous activity was augmented by CoQ10 (p<0.05). CoQ10 also induced enhanced lipid oxidation as shown by the significantly lower respiratory gas exchange ratio (R) and increased fat oxidation during exercise. The results shed some light upon the relationship between the autonomic nervous activity and energy metabolism.

These results suggested that CoQ10 may increase fat oxidation with augmented autonomic nervous activity during low intensity exercise.

J Nutr Sci Vitaminol (Tokyo). 2008 Aug;54(4):286-90. Influence of CoQ10 on Autonomic Nervous Activity and Energy Metabolism during Exercise in Healthy Subjects.

Xealswe
2008-09-18, 10:27
Q10 finns som beståndsdel i mivitotal