Effekten av oligonolintag på kortisolnivåer och relaterade cytokiner

[King Grub]

This study investigated the effects of Oligonol intake on cortisol, interleukin (IL)-1beta, and IL-6 concentrations in the serum at rest and after physical exercise loading. Nineteen healthy sedentary male volunteers participated in this study. The physical characteristics of the subjects were: a mean height of 174.2 +/- 2.7 cm, a mean weight of 74.8 +/- 3.6 kg and a mean age of 22.8 +/- 1.3 years. Each subject received 0.5 L water with Oligonol (100 mg/day) (n = 10) or a placebo (n = 9) daily for four weeks. The body composition, the white blood cell (WBC) and differential counts as well as the serum cortisol, IL-1beta, and IL-6 concentrations were measured before and after Oligonol intake. The cortisol concentration and serum levels of IL-1beta and IL-6 after Oligonol intake were significantly decreased compared to before treatment (P < 0.01, respectively). In addition, the rate of increase of these factors after exercise was decreased compared to the placebo group. There was no change in the WBC and differential cell counts. These results suggest that oral Oligonol intake for four weeks had a significant effect on inhibition of inflammatory markers in healthy young men.

Nutr Res Pract. 2010 Jun;4(3):203-7. The effect of Oligonol intake on cortisol and related cytokines in healthy young men.

[SeTi]

Följdfrågan blir:
Vad kan en vanlig gymmare tjäna på att sänka sina kortisolnivåer?
För att vara specifik, påverkan på prestation och muskeluppbyggnad.

[Oxe]

Grub när du postar upp dom här avancerade sakerna som du hittar skulle du inte vilja skriva en liten basic for dummies variant. För oss som inte förstår bättre.

Frågan är ifall det ens är 10% av forumet som förstår nåt när du postar dom har studierna...

Jag vet inte ens vad oligonol är och i vilken mat som den finns... och blev inte mycket klokare av en googelsökning (självklart enbart sidor på svenska)..

[Medusa]

Oligonol® is a particularly innovative antioxidant and anti-aging nutritional supplement. It contains oligomerised polyphenols - the first supplement in which polyphenol polymers have been successfully converted into oligomers, molecules with superior bioavailability and much greater biological activity
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The polyphenols in Oligonol® have a low molecular weight – they are thus easier to absorb and more bioavailable. Studies comparing Oligonol® with extracts of green tea, apple, grapeseed and pinebark, show that Oligonol:

1. is much more quickly absorbed (as measured by levels of polyphenols in the blood);
2. has greater antioxidant capacity;
3. has superior bioavailability;
4. is rapidly absorbed in humans. Polyphenol blood concentrations increase in a dose-dependent manner during periods of supplementation.

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Oligonol is derived from lychee fruit. Lychee has been a valued fruit renowned for thousands of years for promoting healthy aging. In ancient China, the Emperor’s concubine, Yang Gui Fei, reportedly maintained her breathtaking beauty for all the many years of her life because of lychee which the Emperor horded from all over China for her use only.
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The lychee, from which Oligonol is made, is native to low elevations of the provinces of Southern China but its cultivation has spread over the years through neighboring areas of southeastern Asia. Lychee has a high content of polyphenol polymers and through a patented process, these unique molecules can be made to be more absorbable by the body.
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A proprietary extract of lychee fruit manufactured using a patented technology that boosts polyphenol bioavailability of the product and thereby enhances the product's anti-oxidant capacity.
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Polyphenols are abundantly present in plants and are known for their ant-oxidant and anti-aging properties. Oligonol is produced through a proprietary process that shortens polyphenol polymers into monomers and oligomers to form a unique oligomerized polyphenol, producing greater bio-availability to the body than conventional polyphenols, such as: pine bark, grape seed, apple and green tea.
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Oligonol is shown to be 5 times more bio-available resulting in speedier absorption than conventional polyphenols
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Oligonol decreased more than 10% of the lipid peroxide level in blood and improved lucidity and sleep pattern in a human study.*
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Oligonol was more effective in many parameters in a study on cognitive function than conventional polyphenols.
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Extensive in vivo toxicity studies show Oligonol to be safe with no adverse effects or negative interactions. Laboratory testing also reveals that Oligonol is a stable substance.
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Scientific research reveals that Oligonol is a safe, powerful anti-oxidant that can slow the aging process.* Clinical studies supporting Oligonol as an efficacious healthy aging dietary supplement were conducted in the following areas:

1. Skin improvement (to prevent and reduce wrinkles and freckles)*
2. Blood circulation improvement*
3. Reduction of and fast recovery from fatigue*
4. Metabolic support*
5. Natural, safe, no negative interactions


från http://www.q-o-l.com/cat_antiaging.html

[Frumpish]

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