Effekt av styrketräning med hög och låg belastning på angiogenes

[King Grub]

Resistance training promotes microvasculature expansion; however, it remains unknown how different resistance training programs contribute to angiogenesis. Thus, we recruited experienced resistance trained participants and determined the effect of 12 wk of either high-repetition/low-load or low-repetition/high-load resistance training performed to volitional fatigue on muscle microvasculature. Twenty men performed either a high-repetition (20-25 repetitions, 30-50% of 1RM; n=10) or a low-repetition (8-12 repetitions, 75-90% of 1RM; n=10) resistance training program. Muscle biopsies were taken before and after resistance training, and immunohistochemistry was used to assess fiber-type (I and II) specific microvascular variables. High-repetition/low-load and low-repetition/high-load groups were not different in any variable before resistance training. Both protocols resulted in an increase in capillarization. Specifically, after resistance training the capillary-to-fiber ratio, capillary contacts, capillary-to-fiber perimeter exchange index, were elevated and sharing factor was reduced. These data demonstrate that resistance training performed to volitional failure, using either high-repetition/low-load or low-repetition/high-load, induced similar microvascular adaptations in recreationally resistance trained young men.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 13. Microvascular Adaptations to Resistance Training are Independent of Load in Resistance Trained Young Men.