Sedentary behavior is an emerging risk factor for several cancers. Here, we review the current epidemiologic evidence on sedentary behavior and cancer risk and summarize potential underlying molecular mechanisms.
Recent Findings
High compared to low sedentary behavior is associated with a 28–44% increased risk of colon cancer, a 8–17% increased risk of breast cancer, and a 28–36% increased risk of endometrial cancer. For other cancer sites, the current evidence is insufficient, mainly due to sparse numbers of available studies. Potential underlying biologic mechanisms linking prolonged sedentary behavior to increased cancer risk include metabolic dysfunction, alterations in circulating levels of sex hormones, and low-grade systemic chronic inflammation.
Summary
Prolonged sedentary behavior is positively related to cancers of the colon, breast, and endometrium. For other cancer types, the current evidence is inconclusive. Underlying biological mechanisms are poorly understood and need to be an integral part of future research.
The Influence of Sedentary Behavior on Cancer Risk: Epidemiologic Evidence and Potential Molecular Mechanisms. Current Nutrition Reports, pp 1–8, 18 March 2019.
Det är nog helt enkelt inte min grej att upprepade gånger bli slängd i golvet så skallen och ryggen värker och att ha svettiga, håriga män som bänder runt mina armar, stryper mig och sitter på mitt ansikte.
Om man smaskar i sig massa komplexa kolhydrater samtidigt som man sitter och slöar så kanske det blir plus minus noll? ^^
Mer gröt till folket
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Ursprungligen postat av Diomedea exulans
Det är nog helt enkelt inte min grej att upprepade gånger bli slängd i golvet så skallen och ryggen värker och att ha svettiga, håriga män som bänder runt mina armar, stryper mig och sitter på mitt ansikte.