Prestationshöjande effekter av alfa-glycerylfosforylkolin

[King Grub]

Background

Recent studies have suggested that alpha glycerylphosphorylcholine (A-GPC) may be an effective ergogenic aid. The present study was designed to assess the efficacy of two doses of A-GPC in comparison to placebo and caffeine for increasing countermovement jump performance, isometric strength, and psychomotor function.

Methods

Forty-eight healthy, college aged males volunteered for the present study and underwent baseline assessment of countermovement jump (CMJ), isometric mid thigh pull (IMTP), upper body isometric strength test (UBIST), and psychomotor vigilance (PVT). Following this assessment participants were randomly assigned to groups consisting of 500 mg A-GPC, 250 mg A-GPC, 200 mg Caffeine or Placebo taken daily. Blood samples were collected 1 h and 2 h post initial dose to quantify serum free choline and thyroid stimulating hormone then subjects returned after 7 days of supplementation to repeat CMJ, IMTP, UBIST and PVT.

Results

No differences were noted between groups for IMTP, UBIST or PVT performance. Serum free choline was found to be elevated in the two A-GPC groups as compared to placebo (132% and 59% respectively). Serum TSH was found to be significantly depressed in the 500 mg A-GPC group compared to other treatments (p < 0.04). Group differences were noted for maximum velocity and maximum mechanical power on the CMJ (p < 0.05) with the 250 mg A-GPC group demonstrating the greatest improvements in result.

Conclusions

Based upon this evidence, and previous evidence regarding A-GPC, it should be considered as an emerging ergogenic supplement.

Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance. Journal of the International Society of Sports Nutrition 2017, 14:3.

https://jissn.biomedcentral.com/arti...970-017-0196-5

[Konradsson]

Ett väldigt underskattat tillskott.

Bör påminnas att stora delar av befolkningen ligger under RDI för kolin.

[Aryt]

Länkar till tidigare diskussion om kolin, en del matnyttig information där
http://www.kolozzeum.com/forum/showthread.php?t=232597

Ursprungligen postat av Konradsson

Ett väldigt underskattat tillskott.

Bör påminnas att stora delar av befolkningen ligger under RDI för kolin.

Tyvärr lite dyrt och dåligt utbud.

Tror inte att det finns något etablerat RDI (tekniskt sett), men att intagsnivåerna är lägre än förväntat lämpligt intag.

EFSA är inte helt övertygade
https://www.efsa.europa.eu/en/efsajournal/pub/2056

Conditions and possible restrictions of use
The Panel notes that no dietary reference values for choline have been established in the EU. There
are no reliable intake data and there are no indications of inadequate choline intakes available in the
EU. The Panel also notes that dietary references values (adequate intakes) have been established
outside the EU for different population subgroups. A nutrient content claim has been authorised in
the United States based on the adequate intake for adult males (550 mg of choline per day).