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Gammal 2019-02-11, 09:24   #1
King Grub
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Morgonträning mildrar negativa effekter på hjärnan av stillasittande senare på dagen

Citat:
Preventing declines in cerebral blood flow is important for maintaining optimal brain health with aging. We compared the effects of a morning bout of moderate-intensity exercise, with and without subsequent light-intensity walking breaks from sitting, on cerebral blood flow velocity over 8-hours in older adults. In a randomized crossover trial, overweight/obese older adults (n=12, 2♀, 70±7 years; 30.4±4.3 kg/m2), completed 3 acute conditions (6-day washout); SIT: prolonged sitting (8hr, control); EX+SIT: sitting (1hr), moderate-intensity walking (30min), followed by uninterrupted sitting (6.5hr); EX+BR: sitting (1hr), moderate-intensity walking (30min), followed by sitting (6.5hr) interrupted with 3 minutes of light-intensity walking every 30 minutes. Bilateral middle cerebral artery velocities (MCA v) were determined using transcranial Doppler at 13 time points across the day. The temporal pattern and average MCA v over 8-hours was determined. The pattern of MCA v over 8-hours was a negative linear trend in SIT (p<0.001), but a positive quadratic trend in EX+SIT (p<0.001) and EX+BR (p<0.01). Afternoon time points in SIT were lower than baseline within condition (p≤0.001 for all). A morning dip in MCA v was observed in EX+SIT and EX+BR (p<0.05 relative to baseline), but afternoon time points were not significantly lower than baseline. The average MCA v over 8-hours was higher in EX+SIT than SIT (p=0.007) or EX+BR (p=0.024). Uninterrupted sitting should be avoided, and moderate-intensity exercise should be encouraged for the daily maintenance of cerebral blood flow in older adults. The clinical implications of maintaining adequate cerebral blood flow include the delivery of vital oxygen and nutrients to the brain.
J Appl Physiol (1985). 2019 Feb 7. Morning exercise mitigates the impact of prolonged sitting on cerebral blood flow in older adults.
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