Kollagentillskott för ledskador

[Termy]

https://www.ncbi.nlm.nih.gov/pubmed/30859848
Int J Sport Nutr Exerc Metab. 2019 Mar 12:1-20. doi: 0.1123/ijsnem.2018-0385. [Epub ahead of print] Effects of Different Vitamin-C Enriched Collagen Derivatives on Collagen Synthesis. Lis DM1, Baar K1.

Abstract

Nutritional strategies to improve connective tissue collagen synthesis have garnered significant interest, although the scientific validity of these interventions lags behind their hype. This study was designed to determine the effects of three forms of collagen on N-terminal peptide of procollagen I (PINP) and serum amino acid levels. Ten recreationally active males completed a randomized double-blinded cross-over design study consuming either placebo, 15 g of vitamin C enriched gelatin, hydrolyzed collagen or gummy containing equal parts gelatin and hydrolyzed collagen. Supplements were consumed 1 hour before 6 minutes of jump rope. Blood samples were collected immediately prior to supplement consumption and 4 hours after jump rope. A subset of blood samples were collected for amino acid analysis (n=4) 1 hour after ingestion. Consumption of an equivalent dose of each supplement increased amino acids in the circulation similarly across all interventions. PINP levels tended to increase ~20% from baseline in the gelatin and hydrolyzed collagen interventions but not the placebo or gummy. These results suggest that vitamin C enriched gelatin and hydrolyzed collagen supplementation may improve collagen synthesis when taken 1 hour prior to exercise. However, large variability was observed, which precluded significance for any treatment.