Kolozzeum Forum - Sveriges största träningsforum
Gå tillbaka   Kolozzeum Forum - Sveriges största träningsforum > Träning > Kosttillskott

Svara
 
Ämnesverktyg Visningsalternativ
Gammal 2017-12-05, 09:29   #1
King Grub
Chefsarkitekt Oljebyxor
 
King Grubs avatar
 
Reg.datum: Mar 2002
Ort: Norrtälje
Inlägg: 78 268
Vassleprotein skyddar hjärnan mot åldersrelaterad oxidativ stress & neurodegeneration

Citat:
Whey Protein Concentrate (WPC) is a rich source of sulfur-containing amino acids and is consumed as a functional food, incorporating a wide range of nutritional attributes. The purpose of this study is to evaluate the neuroprotective effect of WPC on rat brain during aging. Young (4 months) and old (24 months) male Wistar rats were supplemented with WPC (300 mg/kg b.w.) for 28 days. Biomarkers of oxidative stress and antioxidant capacity in terms of ferric reducing antioxidant potential (FRAP), lipid hydroperoxide (LHP), total thiol (T-SH), protein carbonyl (PC), reactive oxygen species (ROS), nitric oxide (NO) and acetylcholinesterase activity (AChE) were measured in brain of control and experimental groups. In addition, gene expression and histopathological studies were also performed. The results indicate that WPC augmented the level of FRAP, T-SH and AChE in old rats as compared to the old control. Furthermore, WPC treated groups exhibited significant reduction in LHP, PC, ROS and NO levels in aged rats. WPC supplementation also downregulated the expression of inflammatory markers (TNF-α, IL-1β, IL-6), and upregulated the expression of marker genes associated with autophagy (Atg3, Beclin-1, LC3B) and neurodegeneration (NSE, Synapsin-I, MBP-2). The findings suggested WPC to be a potential functional nutritional food supplement that prevents the progression of age-related oxidative damage in Wistar rats.
Appl Physiol Nutr Metab. 2017 Dec 2. Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration.
__________________


Angående PM-rådgivning!
King Grub är inte uppkopplad   Svara med citat


Svara

Ämnesverktyg
Visningsalternativ

Regler för att posta
Du får inte posta nya ämnen
Du får inte posta svar
Du får inte posta bifogade filer
Du får inte redigera dina inlägg

BB-kod är
Smilies är
[IMG]-kod är
HTML-kod är av

Forumhopp


Alla tider är GMT +1. Klockan är nu 14:36.


Powered by vBulletin® Version 3.8.8
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Svensk översättning av: Anders Pettersson
Copyright 2015, Kolozzeum (TM)