Animaliskt, men inte vegetabiliskt, protein ökar risken att dö i förtid

[King Grub]

Evidence for associations between long-term protein intake with mortality is not consistent. We aimed to examine associations of dietary protein from different sources with all-cause and cause-specific mortality. We followed 7786 participants from three sub-cohorts of the Rotterdam Study, a population-based cohort in the Netherlands. Dietary data were collected using food-frequency questionnaires at baseline (1989-1993, 2000-2001, 2006-2008). Deaths were followed until 2018. Associations were examined using Cox regression. Additionally, we performed a highest versus lowest meta-analysis and a dose-response meta-analysis to summarize results from the Rotterdam Study and previous prospective cohorts. During a median follow-up of 13.0 years, 3589 deaths were documented in the Rotterdam Study. In this cohort, after multivariable adjustment, higher total protein intake was associated with higher all-cause mortality [e.g. highest versus lowest quartile of total protein intake as percentage of energy (Q4 versus Q1), HR = 1.12 (1.01, 1.25)]; mainly explained by higher animal protein intake and CVD mortality [Q4 versus Q1, CVD mortality: 1.28 (1.03, 1.60)]. The association of animal protein intake and CVD was mainly contributed to by protein from meat and dairy. Total plant protein intake was not associated with all-cause or cause-specific mortality, mainly explained by null associations for protein from grains and potatoes; but higher intake of protein from legumes, nuts, vegetables, and fruits was associated with lower risk of all-cause and cause-specific mortality. Findings for total and animal protein intake were corroborated in a meta-analysis of eleven prospective cohort studies including the Rotterdam Study (total 64,306 deaths among 350,452 participants): higher total protein intake was associated with higher all-cause mortality [pooled RR for highest versus lowest quantile 1.05 (1.01, 1.10)]; and for dose-response per 5 energy percent (E%) increment, 1.02 (1.004, 1.04); again mainly driven by an association between animal protein and CVD mortality [highest versus lowest, 1.09 (1.01, 1.18); per 5 E% increment, 1.05 (1.02, 1.09)]. Furthermore, in the meta-analysis a higher plant protein intake was associated with lower all-cause and CVD mortality [e.g. for all-cause mortality, highest versus lowest, 0.93 (0.87, 0.99); per 5 E% increment, 0.87 (0.78, 0.98), for CVD mortality, highest versus lowest 0.86 (0.73, 1.00)]. Evidence from prospective cohort studies to date suggests that total protein intake is positively associated with all-cause mortality, mainly driven by a harmful association of animal protein with CVD mortality. Plant protein intake is inversely associated with all-cause and CVD mortality. Our findings support current dietary recommendations to increase intake of plant protein in place of animal protein.

Dietary Protein Intake and All-Cause and Cause-Specific Mortality: Results From the Rotterdam Study and a Meta-Analysis of Prospective Cohort Studies. Eur J Epidemiol (2020).

https://link.springer.com/article/10...54-020-00607-6

[baggard]

Compared to participants in the lowest quartile of animal protein intake, those in the highest quartile of animal protein had a slightly higher BMI, were more often lower educated, and more likely to smoke. In contrast, compared to the participants in the lowest quartile of plant protein intake, those in the highest quartile of plant protein intake had higher overall diet quality, and were more often highly educated, and less likely to smoke (Table 1, Supplemental Table 3).

Vet inte om din rubrik är så rättvis?

Personerna som käkade mest kött hade också sämre diet och livsstil överlag. Om man ska jämföra mer kött vs mindre kött så är det ju bra om vi har identiska kosthållningar och levnadsvis. (Speciellt när studien utförs genom att man intervjuar de här personerna för infon och de flesta säkert bara höftar till med vad dom käkat)

[GI-Joe]

Ursprungligen postat av baggard

Vet inte om din rubrik är så rättvis?

Personerna som käkade mest kött hade också sämre diet och livsstil överlag. Om man ska jämföra mer kött vs mindre kött så är det ju bra om vi har identiska kosthållningar och levnadsvis. (Speciellt när studien utförs genom att man intervjuar de här personerna för infon och de flesta säkert bara höftar till med vad dom käkat)

Tycker inte studier likt denna ska få redovisas, då det är en helt värdelös jämförelse. Samma visa som när mättat fett blev boven i våran kost.

[Animalisk]

Väldigt torftigt!