[King Grub]

Ja, det verkar stämma.

We have previously found a positive association between milk consumption and prostate cancer risk using meta-analysis to analyze published case-control studies. In the present study, further meta-analysis was conducted to estimate the summary relative risk (RR) between the consumption of milk and dairy products and prostate cancer from cohort studies published between 1966- 2006. We found 18 relevant articles and 13 independent studies were available for our analysis. The summary RR was 1.13 (95% confidence interval = 1.02-1.24) when comparing the highest with the lowest quantile of consumption. The summary RRs by study stratification showed a positive association. A dose-response relationship was identified when combining the studies that partitioned the consumption by quintiles. We also evaluated the effects of some limitations, such as dairy classification, prostate cancer stages and publication bias, in the present study. These findings, together with the previous study, suggest that the consumption of milk and dairy products increases the risk of prostate cancer.

Asia Pac J Clin Nutr. 2007;16(3):467-76. Milk consumption is a risk factor for prostate cancer in Western countries: evidence from cohort studies.

Dietary calcium and supplementary calcium were independently associated with an increased risk. For high-grade prostate cancer (Gleason > or = 7), an association was observed for high versus low calcium intake (RR, 1.89; 95% CI, 1.32-2.71; P(trend) = 0.005), but a nonsignificant, inverse association was observed for organ-confined, low-grade prostate cancer (RR, 0.79; 95% CI, 0.50-1.25; P(trend) = 0.09). In a sample of this cohort, higher calcium intake was associated with lower circulating 1,25(OH)2 vitamin D levels. Our findings suggest that calcium intakes exceeding 1,500 mg/d may be associated with a decrease in differentiation in prostate cancer and ultimately with a higher risk of advanced and fatal prostate cancer.

Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):203-10. A prospective study of calcium intake and incident and fatal prostate cancer.

The multivariate relative risk (RR) of prostate cancer for > or =2,000 mg/day compared to <1,000 mg/day of calcium intake was 1.63 (95% confidence interval (CI), 1.27-2.10; p trend < 0.0001). Total dairy intake was also positively associated with risk of prostate cancer. The multivariate RR of prostate cancer comparing extreme quintiles of intake was 1.26 (95% CI, 1.04-1.51; p trend = 0.03). However, no association with total dairy intake remained after we adjusted for calcium (p trend = 0.17). Findings were similar by stage and grade of prostate cancer. The results from this large prospective study suggest that intake of calcium or some related component contained in dairy foods is associated with increased prostate cancer risk.

Int J Cancer. 2007 Jun 1;120(11):2466-73. A prospective study of dietary calcium, dairy products and prostate cancer risk (Finland).

Calcium intake was an independent predictor of prostate cancer (relative risk (RR) = 1.91, 95 percent confidence interval (CI) 1.23-2.97 for intake > or = 1183 vs. < 825 mg/day), especially for metastatic tumors (RR = 2.64, 95 percent CI 1.24-5.61), controlling for age, family history of prostate cancer, smoking, and total energy and phosphorous intakes. High consumption of dairy products was associated with a 50 percent increased risk of prostate cancer.

Cancer Causes Control. 1998 Dec;9(6):559-66. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer (Sweden).

In our CPS-II Nutrition Cohort, the association between high calcium intake and prostate cancer does not appear to be as strong as reported in previous prospective studies. In the Health Professionals Study, calcium intake (>=2000 mg/day) was strongly associated with prostate cancer risk, with RRs of 1.71, 2.97, and 4.57 for total, advanced, and metastatic prostate cancer. In addition, risk of prostate cancer was independently associated with both dietary and supplemental calcium and with milk intake.

Cancer Epidemiology Biomarkers & Prevention Vol. 12, 597-603, July 2003