Sökes vetenskaplig text om ökat proteinbehov

[Fors]

Hej,

Jag skulle behöva en text, god nog att hänvisa till i ett arbete, där man visar att träning ger förhöjd proteinsyntes, samt behov av snabba kolhydrater.

Tack!

[z_bumbi]

Snabba kolhydrater finns det massor av abstrakt om, "King Grub återhämtning kolhydrater" borde ge ganska mycket träffar.

[JAM]

ja, hela 75 st.
http://www.kolozzeum.com/kolozzeum/search.php?searchid=99859

[King Grub]

En pinfärsk studie:

Am J Physiol Endocrinol Metab. 2004 Nov 23;

The combined ingestion of protein and free leucine with carbohydrate increases post-exercise muscle protein synthesis in vivo in male subjects.

Koopman R, Wagenmakers AJ, Manders RJ, Zorenc AH, Senden JM, Gorselink M, Keizer HA, van Loon LJ.

The present study was designed to determine post-exercise muscle protein synthesis and whole-body protein balance following the combined ingestion of carbohydrate with or without protein and/or free leucine. Eight male subjects were randomly assigned to 3 trials in which they consumed drinks containing either carbohydrate (CHO), carbohydrate and protein (CHO+PRO), or carbohydrate, protein and free leucine (CHO+PRO+leu) following 45 min of resistance exercise. A primed, continuous infusion of L-[ring-(13)C6]phenylalanine was applied, with blood samples and muscle biopsies collected to assess fractional synthetic rate (FSR) in the m. vastus lateralis as well as whole-body protein turnover during 6 h of post-exercise recovery. Plasma insulin response was higher in the CHO+PRO+leu compared to the CHO and CHO+PRO trials (+240+/-19% and +77+/-11%, respectively, P<0.05). Whole-body protein breakdown rates were lower, and whole-body protein synthesis rates were higher in the CHO+PRO and CHO+PRO+leu trials compared to the CHO trial (P<0.05). Addition of leucine in the CHO+PRO+leu trial resulted in a lower protein oxidation rate compared to the CHO+PRO trial. Protein balance was negative during recovery in the CHO trial, but positive in the CHO+PRO and CHO+PRO+leu trials. In the CHO+PRO+leu trial, whole-body net protein balance was significantly greater compared to values observed in the CHO+PRO and CHO trials (P<0.05). Mixed muscle FSR, measured over a 6h period of post-exercise recovery, was significantly greater in the CHO+PRO+leu trial compared to the CHO trial (0.095+/-0.006 %(.)h(-1) vs. 0.061+/-0.008 %(.)h(-1), respectively; P<0.05), with intermediate values observed in the CHO+PRO trial (0.0820 +/- 0.0104 %(.)h(-1)). We conclude that the co-ingestion of protein and leucine stimulates muscle protein synthesis and optimizes whole-body protein balance when compared to the intake of carbohydrate only.

[King Grub]

Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):255-71.

Effect of an amino acid, protein, and carbohydrate mixture on net muscle protein balance after resistance exercise.

Borsheim E, Aarsland A, Wolfe RR.

This study tests the hypotheses that (a) a mixture of whey protein, amino acids (AA), and carbohydrates (CHO) stimulates net muscle protein synthesis to a greater extent than isoenergetic CHO alone after resistance exercise; and (b) that the stimulatory effect of a protein, AA, and CHO mixture will last beyond the 1st hour after intake. Eight subjects participated in 2 trials. In one (PAAC), they ingested 77.4 g CHO, 17.5 g whey protein, and 4.9 g AA 1 hr after resistance exercise. In the other (CON), 100 g CHO was ingested instead. They received a primed constant infusion of L-[2H5]-phenylalanine, and samples from femoral artery and vein, and biopsies from vastus lateralis were obtained. The area under the curve for net uptake of phenylalanine into muscle above pre-drink value was 128+/- 42 mg x leg(- 1) (PAAC) versus 32+/- 10 mg x leg (-1) (CON) for the 3 hr after the drink (p =.04). The net protein balance response to the mixture consisted of two components, one rapid immediate response, and a smaller delayed response about 90 min after drink, whereas in CON only a small delayed response was seen. We conclude that after resistance exercise, a mixture of whey protein, AA, and CHO stimulated muscle protein synthesis to a greater extent than isoenergetic CHO alone. Further, compared to previously reported findings, the addition of protein to an AA+ CHO mixture seems to extend the anabolic effect.

[King Grub]

Exerc Sport Sci Rev. 2003 Jul;31(3):127-31.

Contractile and nutritional regulation of human muscle growth.

Rasmussen BB, Phillips SM.

Resistance exercise and nutritional provision are two independent and major stimuli of muscle protein synthesis and overall muscle growth. The focus of this review is on the regulation of muscle anabolism in humans after resistance exercise, nutritional provision, and a combination of the two.

[AcidSleeper]

Vad gör leucin för kroppen?

[Wooch]

Leucin är en av många aminosyror som utgör byggstenarna i proteiner


Kanske även bör sägas att musklerna består av detta till en viss del och vid intag av detta motverkar man muskelnedbrytning. Nu hoppas jag att det blev rätt. :)

[Sverker]

...och är en grenad aminosyra ( BCAA ) som företrädesvis förbränns i musklerna medan de andra aminosyrorna förbränns i levern.

Om jag inte minns fel så är det leucin som är den aminosyra som stimulerar fram mest insulin vilket är possitivt efter träningen när energin skall fördelas ut till de tränade musklerna.

Alla vassleprotein innehåller mycket leucin.

[AcidSleeper]

Tack för det! artikeln blev så mycket klarare nu! :D

[William]

Om jag inte minns fel så är det leucin som är den aminosyra som stimulerar fram mest insulin vilket är possitivt efter träningen när energin skall fördelas ut till de tränade musklerna.




Jag hade för mig att det var arginin? Dock långt ifrån säker ;)