King Grub
2017-12-13, 10:14
PURPOSE:
To determine the association between 2-minute heart rate recovery (HRR) and cancer risk.
METHODS:
Each participant (5379 women; 8485 men) provided HRR obtained from treadmill tests. The outcome was site-specific cancer.
RESULTS:
Over 9 years of follow-up, 630 cancer events (258 women) were accrued. Slower HRR was associated with increased thyroid cancer risk in women ( P for trend = .0121) and colorectal cancer risk in men ( P for trend = .0034). The lowest HRR (<13 bpm) had higher hazards of thyroid cancer (hazard ratio [HR] = 2.20; 95% CI = 1.28-3.77) in women and colorectal cancer (HR = 3.08; 95% CI = 1.32-7.15) in men. In women, slower HRR and lower proportions of heart rate recovery (PHRR) were associated with higher hazards of thyroid cancer in women and metabolically related cancers (liver and colorectal) in men.
CONCLUSION:
Slower HRR and lower PHRR were independent risk factors for thyroid cancer in women and metabolically related cancers in men.
Asia Pac J Public Health. 2017 Dec 1. Heart Rate Recovery and Cancer Risk: Prospective Cohort Study.
To determine the association between 2-minute heart rate recovery (HRR) and cancer risk.
METHODS:
Each participant (5379 women; 8485 men) provided HRR obtained from treadmill tests. The outcome was site-specific cancer.
RESULTS:
Over 9 years of follow-up, 630 cancer events (258 women) were accrued. Slower HRR was associated with increased thyroid cancer risk in women ( P for trend = .0121) and colorectal cancer risk in men ( P for trend = .0034). The lowest HRR (<13 bpm) had higher hazards of thyroid cancer (hazard ratio [HR] = 2.20; 95% CI = 1.28-3.77) in women and colorectal cancer (HR = 3.08; 95% CI = 1.32-7.15) in men. In women, slower HRR and lower proportions of heart rate recovery (PHRR) were associated with higher hazards of thyroid cancer in women and metabolically related cancers (liver and colorectal) in men.
CONCLUSION:
Slower HRR and lower PHRR were independent risk factors for thyroid cancer in women and metabolically related cancers in men.
Asia Pac J Public Health. 2017 Dec 1. Heart Rate Recovery and Cancer Risk: Prospective Cohort Study.