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[King Grub]

Analgesics are widely used in sport to treat pain and inflammation associated with injury. However, there is growing evidence that some athletes might be taking these substances in an attempt to enhance performance. While the pharmacological action of analgesics and their use in treating pain with and without anti-inflammatory effect is well established, their effect on sport performance is debated. The aim of this review was to evaluate the evidence of whether analgesics are capable of enhancing exercise performance, and if so, to what extent. Paracetamol has been suggested to improve endurance and repeated sprint exercise performance by reducing the activation of higher brain structures involved in pain and cognitive/affective processing. Non-steroidal anti-inflammatory drugs (NSAIDs) affect both central and peripheral body systems, but investigation on their ergogenic effect on muscle strength development have provided equivocal results. The therapeutic use of glucocorticoids is indubitable, but clear evidence exists for a performance enhancing effect following short-term oral administration. Based upon the evidence presented in this review article, the ergogenic benefit of analgesics may warrant further consideration by regulatory bodies. In contrast to the aforementioned analgesics, there is a paucity of research on the use opioids such as tramadol on sporting performance.

PM R. 2017 Aug 3. Analgesics and Sport Performance: Beyond the Pain Modulating Effects.