King Grub
2017-08-07, 21:45
Increasing daily energy expenditure (EE) plays an important role for metabolic health and weight management. Obesity, an epidemic with associated conditions has kept increasing in all age groups for the past three decades. There is no evidence of a decline in overweight and obesity prevalence in any age group for the past 10 years. Capsaicinoids are bioactives from Capsicum extract reported lipolysis, increased energy expenditure, increased lipid oxidation and reduced appetite. Breezing® is a portable device that measures your metabolism using a method called indirect calorimetry. It analyzes your rates of oxygen consumption and carbon dioxide production. Breezing®, a handheld device about the size of a computer mouse, is the world’s first battery-operated portable metabolism tracker that syncs with a smartphone. This innovative device helps people develop a personalized weight management plan based on their own metabolic profile. Resting energy expenditure (REE) affected by factors such as body composition, age, sex, medical conditions and genetics. The purpose of this study is to investigate the effects of capsaicinoids supplement on metabolic rate and heart rate upon the supplementation at rest in healthy subjects. In a single blind, acute, placebo-controlled, crossover open label study and after an initial familiarization visit, 40 subjects (male: n=23; female: n=17; Age: 28.2 ± 5.3 y; body mass index=23.1 ± 3.8lb/in2 ; Body fat (Bio-impedence): 18.6 ± 7.2%) underwent testingsessions with metabolic tracker breezing equipment during which time they consumed either a 2 mg capsaicinoids supplement (100 mg Capsimax®) or placebo, one capsule per day. At least 35 subjects are required to satisfy a power of 0.95 with an α of 0.05. After supplementation, resting energy expenditure (REE) at different time points (Baseline (BL), 1 h, 2 h and 3 hrs and calculated for 24 hr REE), heart rate (HR), and blood pressure (BP) were assessed. The capsaicinoids treatment resulted in significantly (p ≤ 0.05) greater energy expenditure [∆REE% 6.07] vs. placebo. The extrapolated REE changes in 24 hrs for capsaicinoids were 130 kcal/day (7.23%) and placebo was 8 kcal/day (1.17%). There were no significant between-treatment differences for Heart rate (HR). These findings indicate that the thermogenic nutritional supplement could increase resting energy expenditure (REE). Further long term studies are required to explore breezing metabolic tracker use in nutritional studies for weight management.
Capsaicinoids Enhance Metabolic Rate in Normal Healthy Individuals using a Novel Metabolic Tracker Breezing Device-An Open Label Placebo Controlled Acute Study. Obes Open Access 3(2): 2017.
Capsaicinoids Enhance Metabolic Rate in Normal Healthy Individuals using a Novel Metabolic Tracker Breezing Device-An Open Label Placebo Controlled Acute Study. Obes Open Access 3(2): 2017.