King Grub
2017-03-16, 14:28
Background
Increases in skeletal muscle mass can be achieved through resistance exercise training and adequate diet. The recommendation of protein intake for maximize muscle protein synthesis involves 1.5–2.2 g/kg.day−1 or 0.2–0.30 g/kg per meal of high-quality protein source. Protein timing is a dietary strategy designed to optimize the net muscle protein accretion. Timing of protein ingestion in relation to overnight recovery is a topic of recent investigations. Pre-sleep feeding is a time when protein intake may provide a marked benefit to remodel muscle proteins. Thus, the aim of this study is to analyse the clinical trials that evaluated the effects of pre-sleep protein consumption on muscle protein synthesis during overnight recovery.
Methods
A systematic literature search was conducted on PubMed database (English, Spanish and Portuguese) seeking articles published until September 2016 using a combination of the following keywords: ‘sleep’, ‘overnight’, ‘muscle’, and ‘protein’. Clinical trials with human subjects which analyzed the effects of pre-sleep protein intake on overnight protein synthesis were included. Studies characteristics and muscle protein synthesis parameters (‘whole-body protein synthesis’ and ‘mixed-muscle protein fractional synthetic rate’) were appraised.
Results
Eighteen studies were identified through database searching. After eligibility assessment, four studies were selected for the final analysis. Compared with placebo treatment (water), 30 or 40g of protein (casein) intake prior to sleep seems to improve the whole-body protein synthesis rates in healthy adult men during overnight period (7.5 to 9.0 hours) with or without resistance exercise training in the evening before. The studies found no effect of before sleep protein intake on mixed-muscle protein fractional synthetic rate.
Conclusions
The present study is the first systematic review that examines the effects of pre-sleep protein supplementation on muscle protein synthesis rate during overnight period. Overall, these findings suggest that pre-sleep protein intake has benefit effects on overnight whole-body protein synthesis rates. It remains to be established whether ingestion of a moderate amount of protein increases overnight muscle protein synthesis parameters in all populations. Therefore, more high-quality clinical trials are required to confirm these results.
Is there a need of protein ingestion before sleep to maximize muscle hypertrophy? – a systematic review of recent data. ournal of the International Society of Sports Nutrition201714(Suppl 1):8.
Increases in skeletal muscle mass can be achieved through resistance exercise training and adequate diet. The recommendation of protein intake for maximize muscle protein synthesis involves 1.5–2.2 g/kg.day−1 or 0.2–0.30 g/kg per meal of high-quality protein source. Protein timing is a dietary strategy designed to optimize the net muscle protein accretion. Timing of protein ingestion in relation to overnight recovery is a topic of recent investigations. Pre-sleep feeding is a time when protein intake may provide a marked benefit to remodel muscle proteins. Thus, the aim of this study is to analyse the clinical trials that evaluated the effects of pre-sleep protein consumption on muscle protein synthesis during overnight recovery.
Methods
A systematic literature search was conducted on PubMed database (English, Spanish and Portuguese) seeking articles published until September 2016 using a combination of the following keywords: ‘sleep’, ‘overnight’, ‘muscle’, and ‘protein’. Clinical trials with human subjects which analyzed the effects of pre-sleep protein intake on overnight protein synthesis were included. Studies characteristics and muscle protein synthesis parameters (‘whole-body protein synthesis’ and ‘mixed-muscle protein fractional synthetic rate’) were appraised.
Results
Eighteen studies were identified through database searching. After eligibility assessment, four studies were selected for the final analysis. Compared with placebo treatment (water), 30 or 40g of protein (casein) intake prior to sleep seems to improve the whole-body protein synthesis rates in healthy adult men during overnight period (7.5 to 9.0 hours) with or without resistance exercise training in the evening before. The studies found no effect of before sleep protein intake on mixed-muscle protein fractional synthetic rate.
Conclusions
The present study is the first systematic review that examines the effects of pre-sleep protein supplementation on muscle protein synthesis rate during overnight period. Overall, these findings suggest that pre-sleep protein intake has benefit effects on overnight whole-body protein synthesis rates. It remains to be established whether ingestion of a moderate amount of protein increases overnight muscle protein synthesis parameters in all populations. Therefore, more high-quality clinical trials are required to confirm these results.
Is there a need of protein ingestion before sleep to maximize muscle hypertrophy? – a systematic review of recent data. ournal of the International Society of Sports Nutrition201714(Suppl 1):8.