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Visa fullständig version : Rött vin förhindrar akuta negativa vaskulära effekter av rökning


King Grub
2016-09-20, 07:48
Background

Moderate consumption of red wine is associated with less cardiovascular events. We investigated whether red wine consumption counteracts the adverse vascular effects of cigarette smoking.

Methods

Participants smoked three cigarettes, alone or after drinking a titrated volume of red wine. Clinical chemistry, blood counts, plasma cytokine ELISAs, immuno-magnetic separation of CD14+ monocytes for gene expression analysis, fluorescence-activated cell sorting for microparticles, isolation of circulating mononuclear cells to measure telomerase activity were performed and urine cotinine levels were quantified.

Results

Compared to baseline, leukocytosis (p=0.019), neutrophilia (p<0.001), lymphopenia (p<0.001) and eosinopenia (p=0.008) were observed after only smoking. Endothelial as well as platelet-, monocyte- and leukocyte-derived microparticles (p<0.001 each) were elevated. In monocytes, mRNA expression of interleukin-6 (2.6±0.57-fold), tumor necrosis factor alpha (2.2±0.62-fold), and interleukin-1b (2.3±0.44-fold) were up-regulated as was interleukin-6 (1.2±0.12-fold) protein concentration in plasma. Smoking acutely inhibited mononuclear cell telomerase activity. Markers of endothelial damage, inflammation and cellular ageing were completely attenuated by red wine consumption.

Conclusion

Cigarette smoke results in acute endothelial damage, vascular as well as systemic inflammation and indicators of cellular ageing processes in otherwise healthy non-smokers. Pre-treatment with red wine was preventive. The findings underscore the magnitude of acute damage exerted by cigarette smoking in “occasional lifestyle smokers” and demonstrate the potential of red wine as a protective strategy to avert markers of vascular injury.

Red wine prevents the acute negative vascular effects of smoking. The American Journal of Medicine, 12 September 2016.

http://www.amjmed.com/article/S0002-9343(16)30912-3/pdf

kaspen
2016-09-21, 19:17
Det här är ingenting som jag kan någonting om. Men kan det vara så jävla enkelt att rökning ju drar ihop blodkärlen och alkohol utvidgar dem?

Sohlsken
2016-09-21, 22:47
Finns det liknande studier som jämför med annan alkohol, eller andra typer av vin?

kaspen
2016-09-22, 03:37
Finns det liknande studier som jämför med annan alkohol, eller andra typer av vin?


Dom har nog valt rödvin av en anledning. Rödvin och även vindruvsjuice har vissa ämnen som eventuellt kan lindra irritationen/den lindriga inflammationen från rökningen.

Luca Brasi
2016-09-22, 10:44
Dom har nog valt rödvin av en anledning. Rödvin och även vindruvsjuice har vissa ämnen som eventuellt kan lindra irritationen/den lindriga inflammationen från rökningen.

Man borde ha en vodka grupp och en rödvinsgrupp då egentligen.