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Visa fullständig version : Effekten av 6 månaders konditionsträning eller styrketräning på artärfunktion.


tjing
2013-02-02, 00:01
A prospective randomised longitudinal study involving 6-months of endurance or resistance exercise on conduit artery adaptation in humans.

Abstract:

This randomised trial evaluated the impact of different exercise training modalities on conduit artery function and size in healthy volunteers. Young (27±5 years) healthy male subjects were randomised to undertake 6-months of either endurance (ET, n=10) or resistance training (RT, n=13). High-resolution ultrasound was used to determine brachial, femoral and carotid artery diameter and wall thickness (IMT) and femoral and brachial flow-mediated (FMD) and glyceryl trinitrate (GTN) mediated dilation.

Improvements in VO2peak occurred with ET (3.6±0.7 to 3.8±0.6 Lmin-1, P=0.024) but not RT. Upper body muscular strength increased following RT (57.8±17.7 to 69.0±19.5 kg, P<0.001), but not ET. Both groups exhibited increases in lean body mass (ET: 1.4±1.8 kg, RT: 2.3±1.3 kg, P<0.05). RT increased brachial artery resting (3.8±0.5 to 4.1±0.4 mm, P<0.05), peak FMD- (+0.2±0.2 mm, P<0.05) and GTN-mediated (+0.3±0.3 mm, P<0.01) diameters, as well as brachial FMD% (5.1±2.2 to 7.0±3.9%, P<0.05).

No improvements in any brachial parameters were observed following ET. Conversely, ET increased resting (6.2±0.7 to 6.4±0.6 mm, P<0.05), peak FMD- (+0.3±0.3 mm, P<0.05) femoral artery diameters, and femoral FMD-to-GTN% ratio (0.6±0.3 to 1.1±0.8, P<0.05). RT did not induce changes in femoral artery parameters. Carotid artery IMT decreased in response to both forms of training.

These findings indicate that 6 months of supervised exercise training induced changes in brachial and femoral arterial size and function and decreased carotid artery IMT. These impacts of both RT and ET would be expected to translate to decreased cardiovascular risk.

The journal of physiology 2013 Jan 28.

http://www.ncbi.nlm.nih.gov/pubmed/23247114