bollio
2011-12-18, 11:05
Jag gillar studier på grisar för de är ganska lika människor metaboliskt och det går dessutom att kontrollera studien som man vill.
Rapsolja är annars känd som en av oljorna som innehåller mest Vitamin E så den här studien var lite överraskande för mig.
Finns det någon som har sett kritik av den här studien eller ska den accepteras som sanning?
Additional vitamin E required in milk replacer diets that contain canola oil
Frank D. Sauer DVM, PhD , 1, Edward R. Farnworth PhD1, #, Jacqueline M.R. Bélanger PhD1, ‡, John K.G. Kramer PhD1, Ric B. Miller DVM, PhD2, Shigeto Yamashiro DVM, PhD3
Abstract
It is known that ingestion of oils containing polyunsaturated fatty acids (PUFA) of the n-3 and n-6 series results in a high degree of unsaturation in membrane phospholipids which in turn may increase lipid peroxidation, cholesterol oxidation, free radical accumulation and membrane damage. Vitamin E is a powerful inhibitor of lipid peroxidation induced by free radical damage to cell membranes and is an essential component of milk replacers. In the experiments reported here, neonatal piglets raised on canola oil based milk replacer diets supplemented according to NRC regulations, and with an α-tocopherol (mg) to PUFA (g) ratio of 0.49:1, had low α-tocopherol levels in their tissues. Depending on the quantity of iron administered, the piglets showed signs of vitamin E deficiency which ranged from acute, with high mortality, to mild, with only microscopic evidence of hepatocyte dissociation. Piglets raised on a soybean oil based milk replacer diet, supplemented with the same amount of α-tocopherol, and with a ratio of α-tocopherol to PUFA of 0.21:1, showed no signs of vitamin E deficiency and had significantly higher tissue levels of vitamin E than the piglets raised with the canola oil milk replacer. The factor(s) present in canola oil which increased the demand for vitamin E are unknown.
Rapsolja är annars känd som en av oljorna som innehåller mest Vitamin E så den här studien var lite överraskande för mig.
Finns det någon som har sett kritik av den här studien eller ska den accepteras som sanning?
Additional vitamin E required in milk replacer diets that contain canola oil
Frank D. Sauer DVM, PhD , 1, Edward R. Farnworth PhD1, #, Jacqueline M.R. Bélanger PhD1, ‡, John K.G. Kramer PhD1, Ric B. Miller DVM, PhD2, Shigeto Yamashiro DVM, PhD3
Abstract
It is known that ingestion of oils containing polyunsaturated fatty acids (PUFA) of the n-3 and n-6 series results in a high degree of unsaturation in membrane phospholipids which in turn may increase lipid peroxidation, cholesterol oxidation, free radical accumulation and membrane damage. Vitamin E is a powerful inhibitor of lipid peroxidation induced by free radical damage to cell membranes and is an essential component of milk replacers. In the experiments reported here, neonatal piglets raised on canola oil based milk replacer diets supplemented according to NRC regulations, and with an α-tocopherol (mg) to PUFA (g) ratio of 0.49:1, had low α-tocopherol levels in their tissues. Depending on the quantity of iron administered, the piglets showed signs of vitamin E deficiency which ranged from acute, with high mortality, to mild, with only microscopic evidence of hepatocyte dissociation. Piglets raised on a soybean oil based milk replacer diet, supplemented with the same amount of α-tocopherol, and with a ratio of α-tocopherol to PUFA of 0.21:1, showed no signs of vitamin E deficiency and had significantly higher tissue levels of vitamin E than the piglets raised with the canola oil milk replacer. The factor(s) present in canola oil which increased the demand for vitamin E are unknown.