handdator

Visa fullständig version : Skolbarns kognitiva funktion i förhållande till nivåer av omega-3 i tidig ålder


Eddie Vedder
2011-05-19, 15:57
Man kollade nivåer av DHA men även miljögifter hos små inuitbarn för att se hur detta påverkade resultat i olika tester på kognitiv förmåga i skolåldern.

BACKGROUND:

The beneficial effects of prenatal and early postnatal intakes of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) on cognitive development during infancy are well recognized. However, few studies have examined the extent to which these benefits continue to be evident in childhood.
OBJECTIVE:

The aim of this study was to examine the relation of n-3 PUFAs and seafood-contaminant intake with memory function in school-age children from a fish-eating community.
DESIGN:

In a prospective, longitudinal study in Arctic Quebec, we assessed Inuit children (n = 154; mean age: 11.3 y) by using a continuous visual recognition task to measure 2 event-related potential components related to recognition memory processing: the FN400 and the late positive component (LPC). Children were also examined by using 2 well-established neurobehavioral assessments of memory: the Digit span forward from Wechsler Intelligence Scales for Children, 4th edition, and the California Verbal Learning Test-Children's Version.
RESULTS:

Repeated-measures analyses of variance revealed that children with higher cord plasma concentrations of docosahexaenoic acid (DHA), which is an important n-3 PUFA, had a shorter FN400 latency and a larger LPC amplitude; and higher plasma DHA concentrations at the time of testing were associated with increased FN400 amplitude. Cord DHA-related effects were observed regardless of seafood-contaminant amounts. Multiple regression analyses also showed positive associations between cord DHA concentrations and performance on neurobehavioral assessments of memory.
CONCLUSION:

To our knowledge, this study provides the first neurophysiologic and neurobehavioral evidence of long-term beneficial effects of n-3 PUFA intake in utero on memory function in school-age children.

Boucher O et al. Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age. Am J Clin Nutr. 2011 May;93(5):1025-37. Epub 2011 Mar 9.

In conclusion, to our knowledge, this study was the first to use ERP measures of recognition memory to assess the effects of n−3 PUFAs and seafood contaminants in school-age children. The results suggest that prenatal DHA intakes have important long-term beneficial effects for memory processing, and current DHA intakes can also be beneficial. Conversely, prenatal mercury and postnatal PCB exposure were both associated with reductions in ERP response amplitude measures, which indicated adverse effects on memory. The interpretation of these results was supported by our findings that these exposures were associated with performance on well-established neuropsychological memory tasks. Thus, the consumption of food rich in n−3 PUFAs during pregnancy and childhood should be encouraged to optimize cognitive function although, because of the contamination of seafood products by neurotoxic pollutants, caution should be taken when selecting dietary sources of n−3 PUFAs.

Eddie Vedder
2011-06-14, 11:24
Lite mer om barns utveckling i förhållande till tidiga DHA-nivåer:

Abstract

Beneficial effects of perinatal DHA supply on later neurological development have been reported. We assessed the effects of maternal DHA supplementation on the neurological development of their children. Healthy pregnant women from Spain, Germany, and Hungary were randomly assigned to a dietary supplement consisting of either fish oil (FO) (500 mg/d DHA + 150 mg/d EPA), 400 μg/d 5-methyltetrahydrofolate, both, or placebo from wk 20 of gestation until delivery. Fatty acids in plasma and erythrocyte phospholipids (PL) were determined in maternal blood at gestational wk 20 and 30 and in cord and maternal blood at delivery. Neurological development was assessed with the Hempel examination at the age of 4 y and the Touwen examination at 5.5 y. Minor neurological dysfunction, neurological optimality score (NOS), and fluency score did not differ between groups at either age, but the odds of children with the maximal NOS score increased with every unit increment in cord blood DHA level at delivery in plasma PL (95% CI: 1.094-2.262), erythrocyte phosphatidylethanolamine (95% CI: 1.091-2.417), and erythrocyte phosphatidylcholine (95% CI: 1.003-2.643). We conclude that higher DHA levels in cord blood may be related to a better neurological outcome at 5.5 y of age.

Prenatal DHA Status and Neurological Outcome in Children at Age 5.5 Years Are Positively Associated. J Nutr. 2011 Jun;141(6):1216-23. Epub 2011 Apr 27.

begt
2011-06-14, 11:41
Intressant, att det står en del om kvicksilver. Särskilt fet insjöfisk innehåller mycket kvicksilver (även Omega-3), och även metylkvicksilver som är långt farligare. Kvicksilver har en negativ påverkan på nervsystemet och särskilt små barn är känsliga för det. Det kan också leda till kraftigt ökad risk för tidig död hos vuxna män (Salonen et al. 1995).

mikaelj
2011-06-14, 12:28
Då får man öka selenintaget.

Sverker
2011-06-14, 18:19
Du ska använda selen till att binda kviksilvret:confused:



Minst sagt djärvt tilltag:D att neutralisera ett gift med något annat potensiellt gift.

Jag tror det är förnuftigare att INTE äta insjöfisk eller kött från djur som betar kring gruvor och smältverk.

Cerberus
2011-06-14, 19:23
otroligt intressant men har läst antydningar i vetenskap om detta tidigare. Omega 3 is the shit

hejhopp79
2011-06-15, 14:02
Interesting stuff.

Jag tror att man kommer upptäcka mycket mer angående omega-3 och hur viktigt det är

Cerberus
2011-06-16, 12:09
vad jag läst påverkas ens framtids hjärnutveckling makalöst mycket under graviditet och begynnande år i den yttre världen.

oerhört intressant som sagt.