Alpha-gpc/citicholine som tillskott för träning?

[kalle_banan]

Jag såg att ett företag saluförde dessa för personer som tränar, men jag frågar mig vad de kan ha för nytta för en tränande person? A-gpc kan väl eventuellt påverka hgh, men i övrigt har väl inte kolin/acetylkolin något med träning att göra? För som jag förstår blir a-gpc och citikolin acetylkolin i kroppen...? Det vore väl eventuellt om acetylkolinet i teorin ökade antal fibrer som kontraherade?

[Sverker]

Vad är A-gpc ?

[Alone_in_the_dark]

Vad är A-gpc ?

Min vän Google svarar,
L-Alpha Glycerylphosphorylcholine (Alpha GPC, choline alfoscerate):D

[kalle_banan]

Vad är A-gpc ?

Förkortning på alpha-gpc.

[C.E.J.]

Den här läste jag för länge sen, om kolin:

ABSTRACT: Phospholipids are essential components of all biological membranes. Phosphatidylcholine (PC) and Phosphatidylserine (PS) are Phosphatidyl-phospholipids that are required for normal cellular structure and function. The participation in physical activity often challenges a variety of physiological systems; consequently, the ability to maintain normal cellular function during activity can determine sporting performance. The participation in prolonged intense exercise has been shown to reduce circulatory choline concentrations in some individuals. As choline is a pre-cursor to the neurotransmitter Acetylcholine, this finding has encouraged researchers to investigate the hypothesis that supplementation with PC (or choline salts) could enhance sporting performance. Although the available data that evaluates the effects of PC supplementation on performance are equivocal, acute oral supplementation with PC (~0.2 g PC per kg body mass) has been demonstrated to improve performance in a variety of sporting activities where exercise has depleted circulatory choline concentrations. Short term oral supplementation with soy-derived PS (S-PS) has been reported to attenuate circulating cortisol concentrations, improve perceived well-being, and reduce perceived muscle soreness after exercise. More recently, short term oral supplementation (750 mg per day of S-PS for 10 days) has been demonstrated to improve exercise capacity during high intensity cycling and tended to increase performance during intermittent running. Although more research is warranted to determine minimum dietary Phospholipid requirements for optimal sporting performance, these findings suggest that some participants might benefit from dietary interventions that increase the intakes of PC and PS.

J Int Soc Sports Nutr. 2007 Jul 25;4:5.

[JonasX]

Alpha-GPC is a precursor to the neurotransmitter acetylcholine. Clinically, it's been used both orally and intramuscularly to treat Alzheimer's disease, vascular dementia, stroke, transient ischemic attack (TIA), as well as to improve memory, cognitive function, and learning.

Clearly, you don't have to be a physician to see that it has profound effects on the nervous system. However, prior to Dr. Ziegenfuss, not many researchers thought to test alpha-GPC on advanced athletes.

On the other hand, choline, which is a precursor to alpha-GPC, has been tested on athletes and shown to improve athletic performance and endurance.

The thinking is this:

Acetylcholine is a major neurotransmitter that activates muscle contraction. Increasing the amount of acetylcholine (which is depleted by exercise) in cells can therefore keep muscles contracting longer and harder.

http://www.tmuscle.com/free_online_article/sports_body_training_performance_bodybuilding_supp lements/increase_explosive_force_instantly

[Alone_in_the_dark]

Hade den inte också en positiv effekt på dem som har Altzheimers? (Eller har jag drömt nu...?);)

[C.E.J.]

(Eller har jag drömt nu...?);)

Nä, du har bara inte läst tråden särskilt noga: http://www.kolozzeum.com/forum/showpost.php?p=3838734&postcount=6

[Alone_in_the_dark]

Nä, du har bara inte läst tråden särskilt noga: http://www.kolozzeum.com/forum/showpost.php?p=3838734&postcount=6

Du ser... Nu ska jag skälla på Specsavers att de ger för mig svaga glasögon :D

Hittade detta på en amerikansk sida,


Alpha-GPC seems to be safe when used appropriately. It can cause side effects in some people including heartburn, headache, insomnia, dizziness, skin rash, and confusion.

Don't take alpha-GPC if:

You are pregnant or breast-feeding.


Det sista lät ju bra*rolleyes* Hur hittar jag ut ur gymmet o va fan gör jag här:laugh:

[C.E.J.]

Det sista lät ju bra*rolleyes* Hur hittar jag ut ur gymmet o va fan gör jag här:laugh:

Ganska typisk effekt när man tar för mycket stimulanter.

[kalle_banan]

Så det finns på sin höjd indikationer som tyder på att det kan ha effekt för atleter...

Alpha-gpc och citicholine är inga stimulanter f.ö.

[Sverker]

Är det PC och PS ni ska ha så satsa på ägg.


Ja. Allvar. Äggulan är full av fosfolipiderna PC, fosfatidylkolin och PS, fosfatidylserin.
Vill ni ha ett koncentrat så köp lecithin i hälsokostaffären.

[SweLabs]

Helt klart ett mycket spännande ämne.

Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise
Journal of the International Society of Sports Nutrition 2008, 5(Suppl 1):P15doi:10.1186/1550-2783-5-S1-P15

Conclusion
These data indicate that a single 600 mg dose of A-GPC (as AlphaSize™), when administered 90 minutes prior to resistance exercise, increases post-exercise serum GH and peak bench press force. In contrast, A-GPC had no statistically significant effect on peak power, rate of force development, RMR, or cardiovascular hemodynamics (i.e., heart rate and blood pressure). Future work should examine how resistance exercise + A-GPC affect the GH-IGF axis and their associated family of binding proteins.