Multivitamin... IGEN!

[Serenade]

Hej, jag undrar om det t,ex står att en multitablett har 200 RDI av Vitamin E och det dessutom står att man inte ska överskrida daglig dos gäller det genom maten man äter med?

Tack på förhand *rolleyes*

[Eddie Vedder]

Ja det adderas ju från maten och tillskottet. Så får du i dig 100% av RDI från kosten redan så blir det ju 200% till, alltså 300% av RDI. Om det är skadligt i det långa loppet är ju svårt att svara på, just E-vitamin är ett vitamin där man observerat risker vid höga doser under lång tid.

Men det är var högre doser än sådär. En meta-analys där flera studier på vitamin- och antioxidantsupplemnetrering analyserades vars resultat uppmärksammades en del i media förra året:

Rationale: Lung cancer is the leading cause of cancer-related mortality in the United States. Although supplements are used by half the population, limited information is available about their specific effect on lung cancer risk.

Objectives: To explore the association of supplemental multivitamins, vitamin C, vitamin E, and folate with incident lung cancer.

Methods: Prospective cohort of 77,721 men and women aged 50–76 years from Washington State in the VITAL (VITamins And Lifestyle) study. Cases were identified through the Seattle–Puget Sound SEER (Surveillance, Epidemiology, and End Results) cancer registry.

Measurements and Main Results: Hazard ratios (HRs) for incident lung cancer according to 10-year average daily use of supplemental multivitamins, vitamin C, vitamin E, and folate. A total of 521 cases of lung cancer were identified. Adjusting for smoking, age, and sex, there was no inverse association with any supplement. Supplemental vitamin E was associated with a small increased risk of lung cancer (HR, 1.05 for every 100-mg/d increase in dose; 95% confidence interval [CI], 1.00–1.09; P = 0.033). This risk of supplemental vitamin E was largely confined to current smokers (HR, 1.11 for every 100-mg/d increase; 95% CI, 1.03–1.19; P < 0.01) and was greatest for non–small cell lung cancer (HR, 1.07 for every 100-mg/d increase; 95% CI, 1.02–1.12; P = 0.004).

Conclusions: Supplemental multivitamins, vitamin C, vitamin E, and folate were not associated with a decreased risk of lung cancer. Supplemental vitamin E was associated with a small increased risk. Patients should be counseled against using these supplements to prevent lung cancer.

http://ajrccm.atsjournals.org/cgi/content/abstract/177/5/524

Long-Term Use of Supplemental Multivitamins, Vitamin C, Vitamin E, and Folate Does Not Reduce the Risk of Lung Cancer. American Journal of Respiratory and Critical Care Medicine Vol 177. pp. 524-530

[Snakebite]

Lanar traden lite. I det amerikanska market "Solgars" kosttillskott har nastan samtliga multivitamintillskott b-vitamin doser pa over 50mg....sa aven med b6 som ska kunna vara toxid vid hoga doser. Solgar havdar att deras kosttillskott inte bara ska ha RDI av vissa vitaminer/mineraler utan aven kunna ha en terapeuftisk effekt. Vad skulle t.ex. 3800% av b6 ge som inte 100-200% av RDI skulle ge? Tycker det later markligt.