Eddie Vedder
2008-10-29, 07:00
31 överviktiga, men i övrigt friska, personer fick under 12 veckor leva på en medelhavskost med väldigt lågt kolhydratintag.
Personerna skulle vara motiverade till viktnedgång, tidigare ha ätit en daglig kost på >50E% från kolhydrater, ingen träning, inget bruk av alkhol eller tobak bl.a. och dessutom undersöktes leverfunktion och njurar t.ex. De fick äta ad libitum, d.v.s. så mycket de själva ville, sålänge kolhydratintaget var <30g/dag (från grönsaker främst) och minst 30ml olivolja per dag.
Resultat på både viktnedgång och metabola hälsofaktorer såsom blodglukosreglering, kolesterolvärden, blodtryck och triglycerider var mycket positiva.
Background
Ketogenic diets are an effective healthy way of losing weight since they promote a non-atherogenic lipid profile, lower blood pressure and decrease resistance to insulin with an improvement in blood levels of glucose and insulin. On the other hand, Mediterranean diet is well known to be one of the healthiest diets, being the basic ingredients of such diet the olive oil, red wine and vegetables. In Spain the fish is an important component of such diet. The objective of this study was to determine the dietary effects of a protein ketogenic diet rich in olive oil, salad, fish and red wine.
Methods
A prospective study was carried out in 31 obese subjects (22 male and 19 female) with the inclusion criteria whose body mass index and age was 36.46 +/- 2.22 and 38.48+/-2.27, respectively. This Ketogenic diet was called "Spanish Ketogenic Mediterranean Diet" (SKMD) due to the incorporation of virgin olive oil as the principal source of fat ([greater than or equal to]30ml/day), moderate red wine intake (200-400ml/day), green vegetables and salads as the main source of carbohydrates and fish as the main source of proteins. It was an unlimited calorie diet. Statistical differences between the parameters studied before and after the administration of the "Spanish Ketogenic Mediterranean diet" (week 0 and 12) were analyzed by paired Student's t test.
Results
There was an extremely significant (p<0.0001) reduction in body weight (108.62 kg-> 94.48 kg), body mass index (36.46 kg/m2->31.76 kg/m2), systolic blood pressure (125.71 mmHg->109.05 mmHg), diastolic blood pressure (84.52 mmHg-> 75.24 mmHg), total cholesterol (208.24 mg/dl->186.62 mg/dl), triacylglicerols (218.67 mg/dl->113.90 mg/dl) and glucose (109.81 mg/dl-> 93.33 mg/dl). There was a significant (p=0.0167) reduction in LDLc (114.52 mg/dl->105.95 mg/dl) and an extremely significant increase in HDLc (50.10 mg/dl->54.57 mg/dl). The most affected parameter was the triacylglicerols (47.91% of reduction).
Conclusions
The SKMD is safe, an effective way of losing weight, promoting non-atherogenic lipid profiles, lowering blood pressure and improving fasting blood glucose levels. Future research should include a larger sample size, a longer term use and a comparison with other ketogenic diets.
http://www.nutritionj.com/content/pdf/1475-2891-7-30.pdf
Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss. Nutrition Journal 2008, 7:30. 26 October 2008
Personerna skulle vara motiverade till viktnedgång, tidigare ha ätit en daglig kost på >50E% från kolhydrater, ingen träning, inget bruk av alkhol eller tobak bl.a. och dessutom undersöktes leverfunktion och njurar t.ex. De fick äta ad libitum, d.v.s. så mycket de själva ville, sålänge kolhydratintaget var <30g/dag (från grönsaker främst) och minst 30ml olivolja per dag.
Resultat på både viktnedgång och metabola hälsofaktorer såsom blodglukosreglering, kolesterolvärden, blodtryck och triglycerider var mycket positiva.
Background
Ketogenic diets are an effective healthy way of losing weight since they promote a non-atherogenic lipid profile, lower blood pressure and decrease resistance to insulin with an improvement in blood levels of glucose and insulin. On the other hand, Mediterranean diet is well known to be one of the healthiest diets, being the basic ingredients of such diet the olive oil, red wine and vegetables. In Spain the fish is an important component of such diet. The objective of this study was to determine the dietary effects of a protein ketogenic diet rich in olive oil, salad, fish and red wine.
Methods
A prospective study was carried out in 31 obese subjects (22 male and 19 female) with the inclusion criteria whose body mass index and age was 36.46 +/- 2.22 and 38.48+/-2.27, respectively. This Ketogenic diet was called "Spanish Ketogenic Mediterranean Diet" (SKMD) due to the incorporation of virgin olive oil as the principal source of fat ([greater than or equal to]30ml/day), moderate red wine intake (200-400ml/day), green vegetables and salads as the main source of carbohydrates and fish as the main source of proteins. It was an unlimited calorie diet. Statistical differences between the parameters studied before and after the administration of the "Spanish Ketogenic Mediterranean diet" (week 0 and 12) were analyzed by paired Student's t test.
Results
There was an extremely significant (p<0.0001) reduction in body weight (108.62 kg-> 94.48 kg), body mass index (36.46 kg/m2->31.76 kg/m2), systolic blood pressure (125.71 mmHg->109.05 mmHg), diastolic blood pressure (84.52 mmHg-> 75.24 mmHg), total cholesterol (208.24 mg/dl->186.62 mg/dl), triacylglicerols (218.67 mg/dl->113.90 mg/dl) and glucose (109.81 mg/dl-> 93.33 mg/dl). There was a significant (p=0.0167) reduction in LDLc (114.52 mg/dl->105.95 mg/dl) and an extremely significant increase in HDLc (50.10 mg/dl->54.57 mg/dl). The most affected parameter was the triacylglicerols (47.91% of reduction).
Conclusions
The SKMD is safe, an effective way of losing weight, promoting non-atherogenic lipid profiles, lowering blood pressure and improving fasting blood glucose levels. Future research should include a larger sample size, a longer term use and a comparison with other ketogenic diets.
http://www.nutritionj.com/content/pdf/1475-2891-7-30.pdf
Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss. Nutrition Journal 2008, 7:30. 26 October 2008