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Visa fullständig version : Proteintillskott kan ge upphov till fasciainflammation.


King Grub
2008-03-18, 12:08
Fascia and soft tissues, rich in collagen, receptors of pain and capable of significant distention, may be targets of autoimmune inflammatory diseases. We observed fasciitis due to the protein supplement Pure Whey, which has not been reported previously.

Sonography (Sonosite-Titan, 5 to 10 MHz, L-38) was performed on a patient (age, 26 years; body mass index, 38 kg/m) with protein fasciitis. He had developed compact swelling of his forearms, hands, and legs, with skin irregularity and severe disability (without peripheral eosinophilia, normal Ig and ESR 18/hr) after taking Pure Whey, containing L-tryptophan (1.4 g per 100 g of protein). A deep skin biopsy was performed. The thickness of the brachioradial fascia (BRF) was measured and compared with 10 healthy control subjects (men ages 36.7 +/- 8.3 years; body mass index, 26.4 +/- 6.5 kg/m).

The deep skin biopsy showed severe fat interlobular and fascial thickening with mononuclear (noneosinophilic) infiltrate and fibrosis associated with fasciitis. BRF of the 10 healthy men had a thickness of 0.75 +/- 0.19 mm, compared with the patient's 2.4 mm thickened and cleaved BRF. After 2.5 months of corticosteroid therapy (30 mg/d with tapering) and discontinuation of the protein supplement, the patient's BRF returned to a monolayer appearance. Its thickness reduced to normal (0.8 mm), with significant clinical improvement.

This case of noneosinophilic fasciitis associated with ingestion of L-tryptophan-containing protein supplement responded favorably to corticosteroid therapy. Sonography proved to be an effective method to visualize and confirm the fasciitis and to follow the course and therapy.

Am J Med Sci. 2008 Mar;335(3):242-5. Ultrasound imaging of fasciitis due to body-building supplement.

Ola Wallengren
2008-03-18, 12:43
Det finns tydligen kopplingar till intag av tryptofan och utvecklingen av denna sjukdom men jag tycker inte man med själklarhet kan säga att det var just vassleproteinet som var orsaken eftersom det finns fler faktorer som kan påverka.

Citat från studien
A 26-year-old security officer with a body mass index (BMI) of 38 kg/m2 had development of compact “woody” swelling of his forearms (Figure 1), hands, and legs, with skin irregularity and an inability to grip and straighten his fingers after taking Pure Whey containing L-tryptophan (LT) (1.4 g per 100 g of protein). On admission, he reported taking the Pure Whey supplement for 1 year. The Pure Whey instructions recommend taking Pure Whey after training (performed 5 days per week). According to the patient, the first 6 months of therapy passed without complications. He then began taking Pure Whey twice a day every day, at times without a time relationship to training, and soon had the above-noted complaints.

tristan
2008-03-19, 09:18
vad innebär detta med fasciainflammation? Är det kasst?

Gädda
2008-03-19, 09:32
Borde vara väldigt utbrett isf med tanke på hur många som äter vassletillskott.

vesterberg
2008-03-19, 10:07
vad innebär detta med fasciainflammation? Är det kasst?fascia är en bindvävshinna. håller muskler på plats under kontraktion. så, ja, är väl inte det bästa.

Toel
2008-03-19, 12:40
Vilka mängder rörde det sig om? Står bara han intog vassle 2ggr/dag inte hur mycket?

cerial
2008-03-19, 18:03
Ok. Skumläste bara, men de har ett fall här? Det lilla jag kan om vetenskapsteori säger mig att man inte kan dra några allmängiltiga slutsatser av ett så litet urval.